Selected Publications of Dr. Anthony P. Nicholas:
Nicholas AP, Cuello AC, Goldstein M, and Hökfelt T. Glutamate-like immunoreactivity in medulla oblongata catecholamine/substance P neurons. NeuroReport 1: 235-238, 1990.
Nicholas AP and Hancock MB. Projections from the rostral ventrolateral medulla to brainstem monoamine neurons in the rat. Neurosci Lett 122: 91-95, 1991.
Nicholas AP, Pieribone VA, Arvidsson U, and Hökfelt T. Serotonin, substance P and glutamate/ aspartate-like immunoreactivities in medullo-spinal pathways of rat and primate. Neuroscience 48: 545-559, 1992.
Gradin K, Nicholas AP, Hjemdahl P, Svensson T, and Hökfelt T. Contrasting cardiovascular responses from intrathecal administration of epinephrine and norepinephrine in conscious rats: role of alpha-1 and alpha-2 adrenoceptors. J Cardiovasc Pharmacol 20:367-374, 1992.
Nicholas AP, Pieribone V, and Hökfelt T. Distributions of mRNAs for alpha-2 adrenergic receptor subtypes in rat brain: an in situ hybridization study. J Comp Neurol 328:585-604, 1993.
Nicholas AP, Pieribone VA, and Hökfelt T. Cellular localization of mRNA for beta-1 and beta-2 adrenergic receptors in rat brain: an in situ hybridization study. Neuroscience, 56:1023-1039, 1993.
Pieribone VA, Nicholas AP, Dagerlind Å, and Hökfelt T. Distribution of alpha-1 adrenoceptors in rat brain revealed by in situ hybridization experiments utilizing subtype-specific probes. J Neurosci 14:4252-4268, 1994.
Nicholas AP, Pieribone V, Dagerlind Å, Meister B, Elde R, and Hökfelt T. In situ hybridization: a complimentary method to radioligand-mediated autoradiography for localizing adrenergic, alpha-2 receptor-producing cells. In: The Imidazoline Receptor: Pharmacology, Functions, Ligands and Relevance to Biology and Medicine, Ann. N.Y. Acad. Sci., Vol. 763. D.J. Reis, P. Bousquet and A Parini (Eds.) N.Y. Acad. Sci.: New York, 222-242, 1995.
Nicholas AP, Pieribone VA, and Hökfelt T. The distribution and significance of CNS adrenoceptors examined with in situ hybridization. Trends Phamacol Sci 17: 245-255, 1996.
Nicholas, AP. Parkinson's disease, idiopathic. In: Current Psychiatric Diagnosis & Treatment. L.R. Baxter, and R.O. Friedel (Eds.) Williams & Wilkins: Philadelphia, 132-133, 1998.
Nicholas AP, Zhang X, and Hökfelt T. An immunohistochemical investigation of the opioid cell column in lamina X of the male rat lumbosacral spinal cord. Neurosci Lett 270:9-12, 1999.
Nicholas AP, Snow WW, and Thomas TS. Motor responses of alpha-2C adrenergic receptor knockout mice to MPTP. Soc Neurosci (Abstr) 25:111, 1999.
Nicholas AP, Whitaker JN: Preparation of a monoclonal antibody to citrullinated epitopes: Its characterization and some applications to immunohistochemistry in human brain. Glia 37: 328-336, 2002.
Nicholas AP, Gupta KB, McInnis C, Benjamin, Jr. WH, Williams SL, Kern ER: Evidence for Epstein-Barr virus autoantibodies against human brain in demyelinating encephalitis. Neuropathology and Applied Neurobiology 28:498-501, 2002.
Nicholas AP, King JL, Sambandam T, Echols JD, Gupta KB, McInnis C, Whitaker JN: Immunohistochemical localization of citrullinated proteins in adult rat brain. Journal of Comparative Neurology 459:251-266, 2003.
Nicholas AP, Sambandam T, Echols JD, Tourtellotte WW. Increased citrullinated glial fibrillary acidic protein in secondary progressive multiple sclerosis. Journal of Comparative Neurology 473:128-136, 2004.
Nicholas AP, O'Hearn E, Holmes SE, Chen D-T, Margolis RL. Clinical signs and symptoms in a large hereditary spastic paraparesis pedigree with a novel spastin mutation. Movement Disorders 19:641-648, 2004
Sambandam T, Belousova M, Accavitti-Loper MA, Blanquicett C, Guercello V, Raijmakers R, Nicholas AP. Increased peptidylarginine deiminase type II in hypoxic astrocytes. Biochemical and Biophysical Research Communications 325:1324-1329, 2004.
Nicholas AP, Earnst KS, Marson DC: Atypical Hallervorden-Spatz disease with preserved cognition and obtrusive obsessions and compulsions. Movement Disorders 20(7):880-886, 2005 Jul.
Nicholas AP, Sambandam T, Echols JD, Barnum SR. Expression of citrullinated proteins in murine experimental autoimmune encephalomyelitis. Journal of Comparative Neurology 486(3):254-266, 2005 Jun 6.
DeRycke L, Nicholas AP, Cantaert T, Kruithof E, Echols JD, Vandekerckhove B, Veys EM, De Keyser F, Baeten D. Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase are pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity. Arthritis & Rheumatism 52(8):2323-2330, 2005.
Nicholas AP, Earnst KS, Marson DC: Atypical Hallervorden-Spatz disease with preserved cognition and obtrusive obsession and compulsions. Movement Disorders 20(7):880-886, 2005.
Cantaert T, De Rycke L, Bongartz T, Matteson EL, Tak PP, Nicholas AP, Baeten D. Citrullinated proteins in rheumatoid arthritis: Crucial…but not sufficient! Arthritis & Rheumatism 54(11):3381-3389, 2006.
Nicholas AP. Lovodopa-induced hyperactivity in mice treated with 1-methyl-4-phenyl-1,2,36-tetrahydropyridine. Movement Disorders 22(1):99-104, 2007.
Nicholas AP. Levodopa-induced hyperactivity in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Movement Disorders. 2007; 22:99-104.
Keilhoff G, Prell T, Langnaese K, Mawrin C, Simon M, Fansa H, Nicholas AP. Expression pattern of peptidylarginine deiminase in rat and human Schwann cells. Developmental Neurobiology. 2008; 68:101-114.
Nicholas AP, Lubin FD, Hallett PJ, Vattem P, Ravenscroft P, Bezard E, Zhou S, Fox SH, Brotchie JM, Sweatt JD, Standaert DG. Striatal histone modifications in models of levodopa-induced dyskinesia. Journal of Neurochemistry. 2008; 106:486-494.
Nicholas AP, Buck K, Ferger B. Effects of levodopa on striatal monoamines in mice with levodopa-induced hyperactivity. Neuroscience Letters. 2008; in press.