James H. Meador-Woodruff, M.D.

jimmw@uab.edu

Education:

• 9/76-5/80 University of Richmond, Richmond, Virginia; B.S. in Chemistry, minor subject Mathematics (summa cum laude)
• 8/80-5/84 Medical College of Virginia Commonwealth University, Richmond, Virginia; M.D.
• 6/84-6/89 Resident, Department of Psychiatry, University of Michigan
• 7/85-12/89 Postdoctoral Fellow, Mental Health Research Institute, University of Michigan (Laboratories of Huda Akil and Stanley J. Watson)

Academic Appointments with UAB:

• Heman E. Drummond Professor and Chairman, Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham
• Professor of Neurobiology, University of Alabama at Birmingham (secondary)
• Senior Scientist, Civitan International Research Center, University of Alabama at Birmingham
• Senior Scientist, Center for Glial Biology in Medicine, University of Alabama at Birmingham
• Senior Scientist, Comprehensive Neuroscience Center, University of Alabama at Birmingham
• Senior Scientist, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham

People in the Lab:

Assistant Professors:

• Robert McCullumsmith, smithrob@uab.edu
• Rita Cowell, rcowell@uab.edu
• Janusz Tucholski, jtuchol@uab.edu
• Monsheel Sodhi, msodhi@uab.edu

Graduate Students:

• John Hammond, hammondj@uab.edu
• Deborah Bauer, debbauer@uab.edu 
• Adam Funk, adamfunk@uab.edu

Research Technicians:

• Charlotte Hammond (lab manager), chammond@uab.edu
• Jana Drummond, jdrummond@uabmc.edu
• Doug Morgan, jdmorgan@uab.edu

Undergraduate students:

• Sagar Patel, sagp425@yahoo.com
• Basil Bakir, basil@uab.edu

Research Interests:

• Cellular and subcellular alterations of neural circuitry and molecular expression in psychiatric illnesses.
• My laboratory's primary research interest is on understanding how different parts of the brain communicate with other parts via a variety of chemical signals, and how this communication is disrupted in schizophrenia. Our current focus is on studying the expression of the genes encoding the receptors for the neurotransmitters, dopamine and glutamate, within individual cells in the nervous system.

Recent Publications:

McCullumsmith RE, Kristiansen LV, Beneyto M, Scarr E, Dean B, and Meador-Woodruff JH: Decreased NR1, NR2A, and SAP102 Transcript Expression in the Hippocampus in Bipolar Disorder. Brain Research. 1127: 108-118, 2007.

Kristiansen LV, Huerta I, Beneyto M, and Meador-Woodruff JH: NMDA Receptors and Schizophrenia. Current Opinion in Pharmacology. 7: 48-55, 2007.

Beneyto M, Kristiansen LV, Oni-Orisan A, McCullumsmith RE, and Meador-Woodruff JH: Abnormal Glutamate Receptor Expression in the Medial Temporal Lobe in Schizophrenia and Mood Disorders. Neuropsychopharmacology. 32: 1888-1902, 2007.

McCullumsmith RE, Gupta D, Beneyto M, Kreger E, Haroutunian V, Davis KL, Meador-Woodruff JH: Expression of Transcripts for Myelination-Related Genes in the Anterior Cingulate Cortex in Schizophrenia. Schizophrenia Research. 90: 15-27, 2007.

Beneyto M and Meador-Woodruff JH: Lamina-Specific Abnormalities of NMDA Receptor- Associated Protein Transcripts in the Prefrontal Cortex in Schizophrenia and Bipolar Disorder. Neuropsychopharmacology. 33: 2175-2186, 2008.

Oni-Orisan A, Kristiansen LV, Haroutunian V, Meador-Woodruff JH, and McCullumsmith RE: Altered Vesicular Glutamate Transporter Expression in the Anterior Cingulate Cortex in Schizophrenia. Biological Psychiatry. 63: 766-775, 2008.

Bauer D, McCullumsmith RE, and Meador-Woodruff JH: A Role for Glutamate Receptors, Transporters, and Interacting Proteins in Cortical Dysfunction in Schizophrenia. In O'Donnell P (editor): Cortical Deficits in Schizophrenia: From genes to Function. New York: Springer Publishers, pp.113-147, 2008.