Services include custom production of bacterial, animal and plant cells that require physical containment levels up to BSL2 and purification of their products.
- Microbial growth
- flask up to 375 liters
- aerobic, anaerobic or thermophilic
- Separation from culture liquid by filtration or centrifugation
- Disruption of cells by french press or sonication
- Separation of cellular debris.
- Tissue culture
T-flasks (up to 40 x T175)
Spinner flasks (up to 8 x 3 liters)
- Bioprocessing of protein and non-protein biological products including:
- concentration
- fractional precipitation
- column chromatography
- microfiltration
- ultrafiltration
- dialysis
- buffer exchange
small scale solvent extractions
- Product development including all of the above procedures
- Analytical techniques including:
- HPLC
- GC
- Protein electrophoresis
- DNA electrophoresis
- Enzyme assays
- Microbial counts
- Gas analysis
- Private consulting is available
Safety
All operations in the Fermentation Facility meet standards approved by the UAB Biosafety Committee and are supervised by
facility personnel to ensure user and environmental safety.