Date Completed: 2/02/09
Faculty Name: Santosh K. Katiyar, Ph.D.
UAB Department: Dermatology
UAB School: Medicine
Campus Address: Volker Hall 557
Campus Zip: 0019
Telephone: 975-2608
Email Address: skatiyar@uab.edu
Office Fax: 934-5745
Research Program Area: Cancer Chemoprevention
Project Title: Chemoprevention of ultraviolet radiation-induced skin cancer through dietary supplements
Project Status: Already up-and-running
Proposed Start Date: April 13
Proposed End Date: August 28
Number of Weeks of Internship: 16
Number of Interns: 1
Other faculty, staff, or graduate students who may help supervise intern: Research Associate; Postdoctoral Fellows
Expected Number of Work Hours Per Week: 20 hours
Expected Work Schedule for Intern: Flexible, intern can largely set his or her own schedule
Number of hours that preceptor will personally supervise or work with intern: 4-6
Category of Research: Laboratory Research
Cancer Research: Skin
Project Description: Chronic exposure of the skin to solar ultraviolet (UV) radiation has been implicated in several skin diseases including the risk of nonmelanoma and melanoma skin cancers. Approximately 1.3 million new cases of skin cancers are diagnosed every year in the US. Exposure of skin to UV radiation induces inflammation, oxidative stress, DNA damage and suppression of immune reactions which contribute to the development of skin cancer. The use of those dietary agents or phytochemicals which have anti-inflammatory, anti-oxidant or DNA repair capability, can protect the skin from adverse effects of solar UV radiation. We are examining the chemopreventive effects of dietary agents, such as green tea polyphenols, grape seed proanthocyanidins, and some other phytochemical, against the photodamaging effect of UV radiation. A new intern can work on these aspects in my research laboratory. More details on the work prospects can be found on the PubMed under my name.
Intern's Anticipated Duties:
Duty 1: Making reagents
Duty 2: Cell culture study
Duty 3: Animal handling and treatment if like to learn
Preceptor will provide intern with access to the following: computer and printer, laboratory work bench space, equipment needed to complete the project
Likelihood of authoring publications: Very Likely
Background, education, experience, or expertise preferred: Basic Knowlege of Lab Skills; Literature Review Skills; Biochemistry; Nutrition Sciences; Molecular Biology
This faculty member has been a CaRES Preceptor for one summer.
Intern 1: Joi Nichols