Date Completed: 2/6/08
Faculty Name: Rizk El-Galley
UAB Department: Surgery/Urology
UAB School: Medicine
Campus Address: FOT 1105
Campus Zip: 3411
Email Address: firstname.lastname@example.org
Research Program Area: Cancer Control and Population Science
Project Title: Adequate Sampling of the Prostate with Transrerctal Ultrasound Guided Biopsies
Project Status: Already up-and-running
Proposed Start Date: April 14
Proposed End Date: August 29
Number of Weeks of Internship: 16
Number of Interns: 2
Other faculty, staff, or graduate students who may help supervise intern: Jim Gladney; Jimmy Jiang
Expected Number of Work Hours Per Week: 37.5 hours
Expected Work Schedule for Intern: Flexible, intern can largely set his or her own schedule
Category of Research: Clinical (Patient Care) Research
Cancer Research: Prostate
Objective: The number of transrectal protate biopsy cores taken differs among urologists. There is no established standard for the number of cores that provide an adequate sampling of the prostate. It is likely that larger prostates require more biopsies for adequate sampling. We have attempted to find a ratio between the number of biopsies and prostate size that will increase cancer detection rates and reduce unnecessary biopsies.
Methods: A database was constructed for 1024 patients who had undergone transrectal ultrasound guided biopsies (TRUS-Bx) in our institution. It included demographic and clinical data. The prostate volume was divided by the number of biopsies to obtain the volume/biopsy ratio (VBR). Multivariate and univariate logistic regression analyses were performed to detect the best predictors for positive biopsies for adenocarcinoma of the prostate.
This data is in peer review at the Urology journal but the PI would like to add to the abstracted database information for statistical significance.
Intern's Anticipated Duties:
Duty 1: Abstracting patient data for entry to database set
Duty 2: Analyzing data for significance
Duty 3: Paper presentation for publication
Preceptor will provide intern with access to the following: office or desk space; computer and printer; equipment needed to complete project; supplies needed to complete project
Likelihood of authoring publications: Very Likely
Background, education, experience, or expertise preferred: Literature Review Skills; Manuscript Preparation; Scientific Writing Skills; Basic Knowledge of Statistics and Data Management
This faculty member has been a CaRES Preceptor for three or more summers.
Intern 1: Wiley Truss Intern 2: Holly Whitlock